MiXCR: a universal tool for fast and accurate analysis of T- and B- cell receptor repertoire sequencing data

MiXCR is a universal framework that processes big immunome data from raw sequences to quantitated clonotypes. MiXCR efficiently handles paired- and single-end reads, considers sequence quality, corrects PCR errors and identifies germline hypermutations. The software supports both partial- and full-length profiling and employs all available RNA or DNA information, including sequences upstream of V and downstream of J gene segments.

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MiXCR pipeline. The workflow from IG or T-cell receptor data sets to final clonotypes is shown